A number of impotence drugs have been available on the market for some time now. Thanks to them millions of men can enjoy the pleasure of intimate relations and thus live a full life. Who knows, maybe these medications not only brought happiness back to many men’s lives, but even saved a lot of marriages and families.
However, things always can go wrong, and the good can for some reason turn into evil. The same story happened to the impotence drugs. The matter is that some men who used them died. Naturally, those deaths were linked to the medications to fight impotence. To answer the question what exactly happened, what went wrong in every particular case, the scientists had to do much work to make the official conclusions.
The results of the patients’ histories and many clinical studies conducted on the issue concluded that impotence drugs can pose a life of their users to danger if taken in combination with nitrates. The latter are the medicines to fight a heart disorder, known as angina or chest pain. Here belong such medications as:
- all forms of nitroglycerin - sublingual, transdermal, and spray forms (Nitrostat, Nitrolingual, Nitro-Dur, Nitro-BID, Nitrong, Nitro-Time, and others);
- isosorbide mononitrate (Imdur, ISMO, Monoket);
- isosorbide dinitrate (Dilatrate-SR, Isordil, Sorbitrate);
- pentaerythritol tetranitrate;
- erythrityl tetranitrate;
- sodium nitroprusside;
- amyl nitrate (“poppers” used as recreational drugs).
The matter is that impotence drugs, namely sildenafil, vardenafil, and tadalafil, are vasodilators – agents that cause vessels to relax and dilate, which results in insignificant blood pressure decrease. Nitrates are also vasodilators. If the two types of medicines are combined, the pressure of blood can drop to dangerous levels, leading to fainting, stroke, or heart attack, thus, posing a real danger to the life of a user. The signs of hypotension are dizziness, blurred vision, nausea, upset stomach, muscle weakness, and headache.
All the men who are going to take impotence drugs must be aware of their interaction with nitrates. It is recommended that the physicians should not only evaluate the cardiac status of patients for whom they are planning to prescribe impotence medications, but they should explain all the nuances of using them and warn about the possible side effects, interactions, and precautions.
Some scholars stick to the point that patients who take nitrates should not use impotence drugs at all; others say that it is still possible to treat angina and improve sexual health as well. Though the two types of drugs must not be taken together, it is safe to use sildenafil or vardenafil in 24 hours after the nitrates administration. Tadalafil will not interact with anti-angina medications if used in 48 hours.
Anyway, every case is unique and only a professional physician can make the right decision. Sometimes there is no other way out than to deprive oneself of something.
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