Combining SSRIs and NSAIDs can raise upper GI bleeding risk by 75%. Learn why this happens, who’s most at risk, and how to prevent it with simple, evidence-based steps like switching medications or adding a PPI.
SSRIs can increase bleeding risk by depleting serotonin in platelets, impairing clotting. Learn which antidepressants carry the highest risk, how to reduce danger, and what to watch for-without stopping essential treatment.